1-Pyrrolidinecarboxylic acid, 2-[(1R,2R)-3-[[(1R,2S)-2-hydroxy-1-methyl-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-, 1,1-dimethylethyl ester, (2S)-

1-Pyrrolidinecarboxylic acid, 2-[(1R,2R)-3-[[(1R,2S)-2-hydroxy-1-methyl-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-, 1,1-dimethylethyl ester, (2S)-

(S)-tert-butyl 2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate

CAS: 160800-65-7

Molecular Formula: C23H36N2O5

1-Pyrrolidinecarboxylic acid, 2-[(1R,2R)-3-[[(1R,2S)-2-hydroxy-1-methyl-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-, 1,1-dimethylethyl ester, (2S)- - Names and Identifiers

Name	(S)-tert-butyl 2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate
Synonyms	BOC-DAP-NE Boc-Dap-NE BOC-Dap-NE (S)-tert-butyl 2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate 1-Pyrrolidinecarboxylic acid, 2-[(1R,2R)-3-[[(1R,2S)-2-hydroxy-1-methyl-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-, 1,1-dimethylethyl ester, (2S)-
CAS	160800-65-7

1-Pyrrolidinecarboxylic acid, 2-[(1R,2R)-3-[[(1R,2S)-2-hydroxy-1-methyl-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-, 1,1-dimethylethyl ester, (2S)- - Physico-chemical Properties

Molecular Formula	C23H36N2O5
Molar Mass	420.54
Density	1.125±0.06 g/cm3(Predicted)
Melting Point	55-57 °C
Boling Point	589.1±50.0 °C(Predicted)
Solubility	10 mM in DMSO
pKa	13.66±0.20(Predicted)
Storage Condition	-20℃
In vitro study	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
In vivo study	ADCs are composed of Antibodies Linked to ADC cytotoxins via an ADC linker.

1-Pyrrolidinecarboxylic acid, 2-[(1R,2R)-3-[[(1R,2S)-2-hydroxy-1-methyl-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-, 1,1-dimethylethyl ester, (2S)- - Preparation solution concentration reference

	1mg	5mg	10mg
1 mM	2.378 ml	11.889 ml	23.779 ml
5 mM	0.476 ml	2.378 ml	4.756 ml
10 mM	0.238 ml	1.189 ml	2.378 ml
5 mM	0.048 ml	0.238 ml	0.476 ml

Last Update：2024-01-02 23:10:35

1-Pyrrolidinecarboxylic acid, 2-[(1R,2R)-3-[[(1R,2S)-2-hydroxy-1-methyl-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-, 1,1-dimethylethyl ester, (2S)- - Reference Information

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

use	Boc-Dap-NE, a dipeptide, is a cleavable ADC linker used to synthesize antibody-drug conjugates (ADC).
in vivo studies	ADC consists of antibodies that connect ADC cytotoxins through ADC connectors.
biological activity	Boc-Dap-NE is a dipeptide, used as a degradable (cleavable) ADC linker, which can be used to synthesize antibody-coupled drugs (ADC).
target	Cleavable
in vitro study

Last Update：2024-04-10 22:29:15

1-Pyrrolidinecarboxylic acid, 2-[(1R,2R)-3-[[(1R,2S)-2-hydroxy-1-methyl-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-, 1,1-dimethylethyl ester, (2S)-

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Product Name: (S)-tert-butyl 2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate Visit Supplier Webpage Request for quotation
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Shanghai Yuanye Bio-Technology Co., Ltd.

Product Name: (S)-tert-butyl 2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate Visit Supplier Webpage Request for quotation
CAS: 160800-65-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409

Click to send a QQ message

Wechat: 18301782025

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1-Pyrrolidinecarboxylic acid, 2-[(1R,2R)-3-[[(1R,2S)-2-hydroxy-1-methyl-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-, 1,1-dimethylethyl ester, (2S)-

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